Muscle relaxant less sedating
One must wait an additional 2 to 5 minutes to fully evaluate the sedative effect before initiating a procedure or repeating a dose.
Rectal administration: the total dose of midazolam usually ranges from 0.3 to 0.5 mg/kg.For this reason, the use in conscious sedation in children less than 6 months of age is not recommended.• Paediatric patients 6 months to 5 years of age: initial dose 0.05 to 0.1 mg/kg.Adults over 60 years of age In adults over 60 years of age, debilitated or chronically ill patients, the initial dose must be reduced to 0.5-1.0 mg and given 5-10 minutes before the beginning of the procedure.Further doses of 0.5 to 1 mg may be given as necessary.• Paediatric patients 6 to 12 years of age: initial dose 0.025 to 0.05 mg/kg.
A total dose of up to 0.4 mg/kg to a maximum of 10 mg may be necessary.
• CONSCIOUS SEDATION before and during diagnostic or therapeutic procedures with or without local anaesthesia.
• ANAESTHESIA – Premedication before induction of anaesthesia – Induction of anaesthesia – As a sedative components in combined anaesthesia • SEDATION IN INTENSIVE CARE UNITS • CONSCIOUS SEDATION before and during diagnostic or therapeutic procedures with or without local anaesthesia.
The intravenous injection of midazolam should be given slowly, at a rate of approx. Adults below the age of 60 In adults below the age of 60 the initial dose is 2 to 2.5 mg given 5 to 10 minutes before the beginning of the procedure. Mean total doses have been found to range from 3.5 to 7.5 mg.
A total dose greater than 5 mg is usually not necessary.
Since in these patients the peak effect may be reached less rapidly, additional midazolam should be titrated very slowly and carefully. administration: midazolam should be titrated slowly to the desired clinical effect.